What immediately bugs you when watching an episode? Mine is when they transport someone sitting down and they reintegrate in a standing position (or vice versa). Sure, the tech is near magical but my suspension of disbelief pretty much snaps when they do this.
The lack of immortality. Sure, you could go the, “We have found that the distinct possibility of death makes life more meaningful” BS, but really - would it take that much power to have someone step into a transporter each night before bed (like taking a very short shower), get buffered, and then sleep? Next day: “Oh no! Lt. Promiscuous has been decapitated! Oh well, beam her back to life and update her on the last 5 hours and we’re good to go again.”
I get it that for plot purposes, that can’t be a thing. But there should be a very good explanation as to why it’s not being done.
So the episode with scotty in the next generation he invented a way for the pattern to not degrade. Its supposed to be relatively short term and have only so much capacity. Even during transport when their are issues it suggest they can lose the buffer. Im relatively accepting of it on that point.