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Joined 1 month ago
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Cake day: December 21st, 2024

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  • When unacclimatized animals are placed in a cold environment, they will acutely defend their body temperature by means of shivering thermogenesis (muscle contractions), which increases heat production (energy expenditure). However, upon prolonged cold exposure, shivering will gradually decrease, but energy expenditure remains elevated, indicating increased NST

    Interestingly, an older study in humans already showed that prolonged cold exposure (12°C, 8 h/d, 31 days) in healthy men also resulted in a gradual decrease of shivering, while heat production remained elevated (11).

    Before cold acclimation, 94% (16 out of 17) of the subjects showed cold-activated BAT depots, and after cold acclimation, 100% BAT prevalence was observed. Cold acclimation increased upper body BAT activity from 2.4 ± 0.7 to 2.8 ± 0.5 SUV mean (P < 0.01) and detectable BAT volume expanded from 665 ± 451 cc before to 913 ± 458 cc (P < 0.01) afterwards. Analysis of dynamic PET/CT imaging of the supraclavicular region revealed that upon cold acclimation, glucose uptake rate did not increase significantly (6.9 ± 3.0 vs. 7.6 ± 2.5 μmol/min/100 g; P > 0.05).

    Or in normal people speak: People who were exposed to the cold got more brown fat.

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  • Better than waking up at 06:00 after getting to bed at 01:00 after travelling for nearly 20 hours in order to get to a meeting that was supposedly happening at 07:00, but since no one wanted to wake up at 06:00 was actually happening at 08:00.

    That also happens to be the meeting where I learned that “passing out on your computer while looking at animal comics” is “unprofessional”.