Flee means to escape, flea is a parasitic insect

Reference to the video game Baba is You. I haven’t played it but it but you essentially reprogram aspects of the game by moving blocks around. From what I understand, to win you must move whatever block “is you” to whatever block “is win” the player made itself “is win” leaving nothing for “is you” heanse being “youless” a pun on this meme normally saying clueless.