Specifically on what they say:

https://techcommunity.microsoft.com/blog/windows-itpro-blog/ltsc-what-is-it-and-when-should-it-be-used/293181

They intend it for stuff that really is specialty systems or single apps, like ATMs or stuff that drive CAT scans. Not geberal-purpose systems.

Doesn’t mean it won’t work for a whole lot of other people, though.