ASD jab: Chinese scientists reach milestone in revolutionary gene therapy for autism::undefined
when tested on mice
How do they know if a mouse is autistic?
I didn’t even know mice could be autistic.
The headline is so hyperbolic it’s basically a lie. It becomes a little tricky because autism spectrum disorder is kind of a broad category. There are certain diseases that have clear genetic causes, other features to their phenotype besides just autism like features, but may share some aspects of autism spectrum disorder symptoms. So often these get lumped in with autism and patients with those disorders also get a diagnosis of autism spectrum disorder. For instance people with fragile x syndrome commonly get an autism diagnosis, but there’s many other features to it as well.
This article stub if following a link at the end is referencing a gene called shank3. It’s not involved in most people classified as having autism spectrum disorder. Mutations in shank3 causes a distinct disorder called Phelan-McDermid syndrome that causes severe intellectual disability, dysmorphic features, autism like features, motor issues, and abnormalities across multiple body systems. Shank3 mutations have also been linked with some cases of schizophrenia. A small minority of people with a diagnosis of autism spectrum disorder have shank3 mutations that may be responsible or pre disposing. So they are testing a gene therapy in mice engineered to have shank3 mutations. Which in humans can have a broad array of phenotypes depending on the mutation, many devastating and severe, some phenotypes of which include autism like features. This will not be very applicable to the vast majority of people classified as having an autism spectrum disorder.
You know those vast cities in China full of brand-new, empty buildings that keep showing up in the news? They’re empty because China doesn’t have enough neurotypical people who could master the sales skills to fill them. This drug is a last-ditch attempt to fill that gap, at the potential expense of sacrificing some engineering capacity.
Hello Genism my old friend
Do we really need to have the debate about ASD not needing to be “cured”, again ?
Do you include folks with level 3 non verbal autism with greater epilepsy frequency and self harm in the group that doesn’t need a therapy?
Imagine a world more inclusive, for them, first, then ask that question. Imagine if the world could be made more comfortable and less traumatic and painful, for them. And there are some who are of that category that do just fine. So do we force them to change too?
As a neuro-divergent person I have two words: fuck you.
I’d gladly take a shot to make my biochemistry change. It sucks. And my issues are trivial compared to autism.
Holy shit, for real.
If I could’ve taken a shot to make it go away and lead a healthy emotional life I would’ve done that in a heartbeat. It sucks so much to be around healthy people and know you’ll never be like them. I don’t resent them, in fact I’m happy for them, but holy shit the envy hurts so much.
Yes, because we still got things we wouldn’t have without those people. Because some are barely functioning doesn’t mean they don’t function. And they’re so different than most people than they bring entirely different things to humanity.
It is also an obvious slippery slope to Genism and don’t even try to tell me that humanity can control itself and that this won’t be used the wrong way.
Either you know it will, or you’re clueless about the horrors humanity exacts.
What they bring is suffering. No one ever wishes for a non responsible child. No one wants their child to be the “special one”. No one wants all the hardship it brings. Even the proxy Munchausen prefers to have a functioning level so they don’t have to do the work. No one wants to be tested by a “greater power” (random gene selection) especially not the sick little being that Teoretically Could be cured but there are people like you who like to decide stuff for OTHERS. How much time do you spend at orphanage with special needs? How much contact do you have to sit on the high horse and try to be god? How much time and money do you spend on personally helping the kids? How many diapers did you change to get to this opinion?
Gene thereapy has a right to exist. And with everything else as humans, we will abuse it to the limit. The problem is not the cure but the mindset. And your pretentious preaching won’t bring conversation only suffering. You are not helping.
You recognize humans will abuse it and then say I’m not helping. I was gonna say that you’re missing the point but as I read more and more, I see you just choose to ignore it, great cognitive dissonance here.
Let me guess you are anti abortion too.
That doesn’t relate in any way and no. Try again to have a point to make.
This be end very bad
You mean to say : “This will end very badly”. How do you say it in your native language ?
Mujico sounds spanish to me, using an app though so can’t actually visit that instance to have a look…
Hi lemann,
I am reading your answer to my comment and I am wondering if maybe you are trying to answer to someone else’s comment (?).
(thanks to @idiomaddict@lemmy.world …now I get lemann’s meaning)
What the actual fuck
