Could you imagine a Voyager where the ship is no longer constantly running towards home? One where they have to stay and gather materials to get their warp 10 drive working. The species they meet will be the same species around a few seasons later, and the relationships they build with them matter. Maybe stasis isn’t good enough, and they have to hold everyone in a transporter buffer, which means rebuilding huge sections of the ship to support having all the crew inside transporters at once. They expect this to take years, but it’s still by far the shortest way home. A few shuttles get modified and they send couriers back to the alpha quadrant. So they have some contact with Star Fleet, but it’s not as simple as opening a channel.

If there’s only enough story material here to support a few seasons, then maybe something comes up that means they have to go back and fix it. Maybe some Borg shit. Make up a reason to keep the Maquis crew around (not like Star Fleet gives a shit once the Dominion War is underway).

Good thing they never gave us that nightmare of a show.